Sunday, July 10, 2016

Odorant receptor movie

Had some fun today creating a short animation showing how an odorant activates an ion channel. 

In the animation, the odorant (red pentagon) attaches to an odorant receptor (purple). Note that the odorant receptor has 7 parts attached to each other. Each part crosses the cell membrane (grey) so part of the receptor is outside the cell, and part inside. 

Once the odorant attaches to the receptor, the last of these 7 parts changes shape, activating the 3-part G-protein (green) attached to the receptor. One part of the G-protein separates and initiates a series of reactions (green arrow) that cause an ion channel to open, and calcium and sodium ions(blue and yellow) flow into the cell. The cell can then send an electrical signal to the brain.



Let me know what you think!

No comments:

Post a Comment